Parathyroidectomy or Calcimimetic to Treat Hypercalcemia after Kidney Transplantation?
نویسندگان
چکیده
Masafumi Fukagawa* and Tilman B. Drüeke *Division of Nephrology, Endocrinology, and Metabolism, Tokai University School of Medicine, Isehara, Japan; and Institut National de la Santé et de la Recherche Médicale Unit 1018, Team 5, Centre de Recherche en Epidémiologie et Santé des Populations, Hôpital Paul Brousse, Paris-Sud University and Versailles Saint-Quentin-enYvelines University (Paris-Ile-de-France-Ouest University), Villejuif, France
منابع مشابه
Clinical Impact of Hypercalcemia in Kidney Transplant
Hypercalcemia (HC) has been variably reported in kidney transplanted (KTx) recipients (5-15%). Calcium levels peak around the 3rd month after KTx and thereafter slightly reduce and stabilize. Though many factors have been claimed to induce HC after KTx, the persistence of posttransplant hyperparathyroidism (PT-HPT) of moderate-severe degree is universally considered the first causal factor. Tho...
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BACKGROUND Calcimimetic agents lower serum parathyroid hormone levels in people with chronic kidney disease (CKD), but treatment effects on patient-relevant outcomes are uncertain. We conducted a systematic review and meta-analysis to summarize the benefits and harms of calcimimetic therapy in adults with CKD and used cumulative meta-analysis to identify how evidence for calcimimetic treatment ...
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INTRODUCTION Kidney transplantation corrects endocrine imbalances. Nevertheless, these early favorable events are not always followed by rapid normalization of parathyroid hormone secretion. A possible deleterious effect of parathyroidectomy on kidney transplant function has been reported. This study aimed to compare acute and longterm renal changes after total parathyroidectomy with those occu...
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Background. The calcimimetic, cinacalcet, is approved for treating secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) on dialysis. Biochemical profiles and clinical outcomes in patients discontinuing cinacalcet at kidney transplantation have not been previously described.Methods. We performed a retrospective observational study evaluating post-transplant biochemi...
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BACKGROUND Hyperparathyroidism is uncommon in adolescence and is more likely to persist after parathyroidectomy than in adults. Cinacalcet HCl is a new calcimimetic that has been used successfully for the treatment of primary and secondary hyperparathyroidism in adults, but its use in adolescents has not been reported. CASE A 16 year-old male presented with hypercalcemia that had persisted fo...
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ورودعنوان ژورنال:
- Journal of the American Society of Nephrology : JASN
دوره 27 8 شماره
صفحات -
تاریخ انتشار 2016